Molecular and cellular factors control signal transduction via switchable allosteric modulator proteins (SAMPs)
نویسندگان
چکیده
منابع مشابه
Allosteric proteins and cellular control systems.
The biological activity of many proteins is controlled by specific metabolites which do not interact directly with the substrates or products of the reactions. The effect of these regulatory agents appears to result exclusively from a conformational alteration (allosteric transition) induced in the protein when it binds the agent. It is suggested that this mechanism plays an essential role in t...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2016
ISSN: 1752-0509
DOI: 10.1186/s12918-016-0274-3